Profile
Graeme Dykes
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About Me:
I have over 20+ years as a Medicinal Chemist. When I have free time, I love to watch movies, catch up on my reading or have a go at whipping something up in the kitchen.
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I grew up in a small village in Perthshire, Scotland. From there I moved to St. Andrews, Manchester, Nottingham and Cambridge. In 2000, I began what would turn out to be a 15-year overseas adventure. First, I relocated to Uppsala in Sweden and from there to Antwerp in Belgium> During my time in Belgium, I also had a 6-month stay in Tübingen, Germany. From Belgium, I moved to Singapore. After that, I returned to the UK.
As I have always had a commute to my various workplaces, I like to listen to audiobooks. I try to rotate through detective stories (e.g. Ian Rankin, Quintin Jardine, Agatha Christie and Arthur Conan-Doyle) non-fiction (Daniel Kahneman, Matt Parker, Stephen J. Dubner, Hans Rosling) and science fiction (e.g. James S.A. Corey, Peter F. Hamilton, Greg Bear, Andy Weir)
Whenever I can, I like to take photos both with my main camera and smartphone. I am always trying to take better pictures, on purpose.
Cars have been a lifelong passion for me. I have successfully completed the Institute for Advanced Driving test. As well as skid-pan training and a supercar track day, I have driven my own car around the Nürburgring.
I am not very active anymore but I used to swim and cycle a lot. In Sweden, I was a Dragonboat racer for several years and even captain of the team on my last outing.
Every week, I take part in “Jay’s Virtual Pub Quiz” and chase that elusive perfect 50/50!
https://www.youtube.com/c/thevirtualpubquiz
I also volunteer at Reading Central Library as part of the Get Online program.
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My pronouns are:
He/Him
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My Work:
Since 2021, I have been working as Senior Chemist at Fleet Bioprocessing Limited.
My work involves using my skills in organic chemistry to precisely attach a small molecule to an antibody or other protein (“Bioconjugation”). These products are found in the devices used to test for viruses (e.g.SARS-COV-2) or bacteria (e.g. Listeria, Salmonella). -
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My current role is part of the manufacture of specialised molecules for other companies
This involves talking with customers to help determine what they need from the product and in what form it will be sent to them. I plan and then carry out experiments to make the products. I need to ensure that I can correctly identify what I have made and how pure it is (some cleanup is almost always needed!). Everything is carefully recorded in a lab notebook and checked. Finally, the products are sent to the customers.
Previously, I worked as a Medicinal Chemist attempting to make new drugs. Once again, organic chemistry was central to this job. However, I worked in a team of many different types of scientists:
- Computational chemists- made computer models to help design my new molecules.
- Biologists – designed experiments to test new molecules, both in isolated cells and live animals.
- Pharmacologists- found out how these new molecules affected living material and how, in turn, that affected the molecules.
- Process chemists – streamline the way of making the molecules such that they can be made in Kg amounts rather than mg!
- Patent lawyers – prepare the legal documents which allow products to be sold.
The projects I have worked on were designed to discover new medicines for diseases such as diabetes, cancer, weight problems, bone diseases, and brain diseases (e.g Motor Neuron disease, as suffered by the late Prof. Hawking).
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My Typical Day:
As I eat my breakfast cereal, I try to warm up my brain with smartphone games (e.g. Wordle, Heardle and Framed).
I work a full week, from 09:00 to 17:00. My day is mostly spent in the lab, carrying out experiments. However, there are “admin” days when I am mostly planning my work or finishing the write-up.
There is constant interaction with my colleagues as we help one another complete our tasks. We are a small team and need to support one another.
There are also tasks to ensure that the lab is kept in good running order.
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My commute is about 30mins and I usually arrive by 08:30. While my tea is brewing, I “wake up” the lab:
- Turn on lights and machines
- Check on overnight experiments
- Make some fresh solutions.
- Take items out of the fridge or freezer and allow them to warm up before use.
I will usually check my email and look at my plan for the day (meetings, phone calls, etc) before starting my lab work. Some days, there are very carefully timed activities within the experiments.
Throughout the day, I will return to my desk to check emails or contribute to discussions with my colleagues.
Lunchtime is flexible for me and depends on what stage my practical work has reached. When the weather is nice, I sit outside and chat with my colleagues.
The labs usually close at around 17:00 so I need to make sure my tasks are completed and any overnight experiments are running safely.
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What I'd do with the prize money:
I would donate the prize money to create a workshop that brings professional scientists into a school.
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Education:
I studied for my O’grades, Highers and CSYS at Perth Academy.
Next, I studied for my degree at The University of St. Andrews, where I was awarded the Elizabeth Soutar prize. As part of this degree course, I completed a six-month industrial placement at Jealott’s Hill (formerly ICI Agrochemicals). At this point, I also joined The Royal Society of Chemistry (RSC).
I obtained first my Master’s and my Doctorate at the University of Manchester. This was supported through the CASE award scheme and my industrial supervisor was based at Tonbridge ( formerly SmithKline Beecham). I successfully upgraded my membership in the RSC to gain the designation of Chartered Chemist.
My post-doctoral fellowship (“post-doc”) was at the Chemistry department of The University of Nottingham.
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Qualifications:
SCE Ordinary Grades:
English, Mathematics, Arithmetic, French, Latin, Classical Studies, Geography, Chemistry, Biology, Physics,
SCE Higher Grades:
English, Mathematics, French, Chemistry, Physics
SCE CSYS:
Chemistry, Physics, Maths (Paper 2)
BSc (HONS): Chemistry, Firstly Class, University of St. Andrews.
MSc. : Organic Chemistry, University of Manchester.
Ph.D.: Organic Chemistry, University of Manchester.
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Work History:
For my first job, I worked at the John Menzies store in Perth, on Saturdays.
While at the University of St. Andrews, I completed mini-research projects for Dr. Nigel Botting and Dr. Kenneth Harris.
After my “Post-Doc”, I joined Chiroscience in Cambridge to work as a medicinal chemist, in the area of cancer treatments.
In 2000, I moved to Uppsala, Sweden, to work for Pharmacia Corp. After a year this became a new company, Biovitrum AB. I spent 5 years working on new treatments for metabolic diseases.
Next, I joined Galapagos NV, based in Mechelen, Belgium. My role changed from a medicinal chemist to a team- and then group- leader in medicinal chemistry. As well as planning the progress of my project, I supervised a team of 5 international medicinal chemists.
From Belgium, I joined GSK in Singapore, as an Investigator on diseases of the central nervous system. When the facility was closed, I returned to the UK.
I spent a year at GSK in Stevenage working on treatments for inflammatory diseases.
Most recently, I joined Fleet Bioprocessing Limited based near Harley Wintney in Hampshire
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Current Job:
Senior Chemist at Fleet Bioprocessing Limited
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Employer:
Fleet Bioprocessing Limited, based near Harley Wintney in Hampshire.
https://www.fleetbioprocessing.co.uk/
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My Interview
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How would you describe yourself in 3 words?
makes new drugs
What did you want to be after you left school?
A chemist, always!
Were you ever in trouble at school?
Got the belt once for forgetting to bring in my homework.
If you weren't doing this job, what would you choose instead?
WRC rally driver
Who is your favourite singer or band?
It changes. Probably Shania Twain at the moment
What's your favourite food?
Hard to choose just one. Love a good steak pie, pizza, Dim Sum
If you had 3 wishes for yourself what would they be? - be honest!
Health, happiness and prosperity for me, my family and my friends
Tell us a joke.
Don't trust atoms! They make up everything!
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